CMS4Vent

About

This project aims to research and standardize the use of digital patient models as a variant of computer-based modelling and simulation (CM&S) in medical technology. The aim is to create an alternative to time-consuming and expensive animal experiments and at the same time more precise, resource-saving and ethically acceptable solutions for the development of new ventilation technologies.

Opportunity

The approval of new functions in medical technology often requires complex and cost-intensive animal testing, which is also being viewed increasingly critically from an ethical perspective. This contradicts the principles of the 3R concept (Replace, Reduce, Refine), which aims to avoid animal experiments, reduce their number and minimize the burden on animals. To meet these challenges, innovative methods are needed that offer a reliable and ethically acceptable alternative.

Solution/Product description

One promising approach is the use of in silico trials, in which computer-based models and simulations (CM&S) are used instead of animal testing. These procedures enable the digital evaluation of innovative functions under realistic conditions. In contrast to medical technology, these are already being used in the pharmaceutical industry and show how in silico trials can reduce costs, accelerate development processes and improve ethical standards at the same time.

Why Us

A key advantage is the active co-design of a European normative and regulatory framework for the use of CM&S methods. This creates a reliable basis for the safe and standardized use of digital simulations in medical technology. In addition, with a verified and validated digital patient simulator for ventilation research, an innovative solution is being developed that largely replaces animal testing and enables a more precise, ethically justifiable and resource-saving evaluation of new ventilation technologies.