Hyperthermia

About

Magnetic Particle Imaging (MPI)-guided magnetic hyperthermia is an emerging cancer treatment strategy that combines real-time imaging with precision heat delivery. Utilizing magnetic nanoparticles (MNPs), MPI provides quantitative, high-resolution images that guide the application of an alternating magnetic field to selectively heat tumors. This approach enables accurate thermal dosing while sparing surrounding healthy tissues, allowing for personalized treatment planning and improved therapeutic outcomes. MPI-guided hyperthermia represents a promising advancement in non-invasive, image-guided cancer therapy.

Opportunity

MPI-guided magnetic hyperthermia offers the unique opportunity to achieve precise, real-time tumor heating guided by accurate nanoparticle quantification. This combination overcomes key limitations of conventional hyperthermia, such as poor targeting and lack of temperature control. It enables personalized treatment by dynamically adjusting thermal dosing based on nanoparticle distribution, minimizing off-target damage and enhancing therapeutic efficacy—advancing non-invasive cancer therapy with greater precision and safety.

Solution/Product description

Coil system will be designed to generate an alternating magnetic field to enable magnetic hyperthermia. The systems can be designed to be integrable for MPI systems to form a theranostic platform which is capable to perform MPI-guided magnetic hyperthermia. The localized heating is realized with the selection field of the MPI system, while the multi-contrast MPI provides the real-time temperature feedback of the therapy.

Why Us

With many years of experience in the development and manufacture of magnetic hyperthermia systems, we offer in-depth expertise and high quality. We have cooperation with an established partner company Bruker BioSpin, where we develop magnetic hyperthermia systems as an add-on solution for their preclinical MPI scanners. University clinic Freiburg has already been using our product successfully. The same product will be delievered to Helmut-Schmidt-Universität / Universität der Bundeswehr in Hamburg soon. In addition, we offer customized designs that can be individually adapted to specific requirements for demanding applications in research and industry.