Imaging - Manipulation - Hyperthermia
With magnetic methods in medicine, conventional therapy and diagnostic approaches can be supplemented or expanded with non-invasive, radiation-free alternatives. Magnetic fields enable both the contact-free movement of the smallest objects in space and the imaging of physiological processes via the detection of nanoparticles
This novel imaging method Magnetic Particle Imaging (MPI) can quantitatively measure and image the three-dimensional distribution and concentration of magnetic nanoparticles with high spatial and temporal resolution and high sensitivity. MPI enables real-time, three-dimensional visualisation of particles and objects without the use of ionising radiation.
The control of the smallest magnetic devices with externally applied magnetic fields can become an important tool in the field of minimally invasive therapy, as it could enable operations to be performed even more gently and drugs to be administered in an even more targeted manner. For precise and safe application, however, magnetic manipulation requires precise monitoring of the movement process of the manipulated objects. In addition to clinically established methods such as X-ray-based imaging, MRI or ultrasound, magnetic particle imaging is particularly suitable. In combination with heating by high-frequency magnetic fields (hyperthermia), further therapeutic effects can be achieved
The area of magnetic methods at Fraunhofer IMTE is concerned with the new and further development of various concepts for MPI systems for clinical and preclinical imaging, as well as systems for the testing and characterisation of nanoparticles. In combination with the other research areas, this results in a holistic approach of innovative magnetic processes in medical technology.