Continuous Flow In-situ Magnetic Particle Spectrometer (CF-INSPECT)

About

The Continuous Flow In-situ Magnetic Particle Spectrometer (CF-INSPECT) builds on the strengths of the standard INSPECT system, with added advantages specifically designed for continuous-flow systems. It is a specialized research platform primarily used for real-time monitoring, characterization of MNPs and for performing synthesis in flow. The device has an in-built 5 channel MPS system for quality analysis at different time points. The device primarily consists of 5 channels consisting of pumps, valves and flow sensors for monitoring the raw materials needed for the synthesis. It is programmable, autonomous, in-situ, cost effective, user friendly and have highly sensitive capabilities.

Opportunity

Conventional MPS has a very small measurement chamber (max. few µl) and can only measure magnetic properties after the completion of the synthesis therefore, most of the synthesis is left unobserved and there is no data for the nucleation and growth of the magnetic nanoparticles (MNPs). Moreover, for nucleation and growth analysis the gold standard is Transmission electron microscopy (TEM) and X-ray spectroscopy. Both these devices are costly, require user expertise and require special measurement chambers. Moreover, under standard chemical conditions, synthesis is typically carried out in relatively large volumes (several milliliters) and requires several hours to complete.

Solution/Product description

CF-INSPECT is a platform designed for the rapid and continuous synthesis of magnetic nanoparticles (MNPs), enabling real-time adjustment of chemical parameters. It can be integrated with AI systems for synthesis analysis and predictive modelling. The device features two fully controllable environments for both heating and cooling, supporting temperatures ranging from 1 °C to 80 °C—ideal for coprecipitation-based synthesis.

CF-INSPECT is equipped with five programmable channels for raw material selection, supporting flow rates between 5 and 8,000 μl/min at a pressure of 500 mbar. To monitor changes in magnetic properties during synthesis, it includes a five-channel Magnetic Particle Spectroscopy (MPS) system with user-defined field strengths and sinusoidal excitation at 25 kHz.

Why Us

• Dynamic Parameter Tuning: The ability to adjust chemical parameters during synthesis allows rapid optimization of reaction conditions.
• Process Flexibility: You can quickly test and compare synthesis protocols without starting from scratch each time.
• AI integration enables real-time data analysis, pattern recognition, and predictive modeling for better synthesis outcomes.
• Supports production at both small and moderate scales, suitable for R&D and potentially for early-stage manufacturing.
• Continuous operation reduces downtime between synthesis runs and accelerates experimental throughput.
• Reduces human error and provides an efficient workflow without a need of user expertise. 
• All the parameters like temperature control, flow rates, dosing etc. can be easily controlled with a software interface